Description

Ethyl 6-Fluoro-4-Hydroxy-2-Naphthoate is a high-purity fluorinated naphthoate ester, a key synthetic intermediate prized for its unique molecular architecture. Its value lies in providing a versatile chemical handle for constructing complex molecules, particularly in advanced pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and ester functionalities into target structures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators, where the fluorine atom can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or precursor for synthesizing advanced polymers, liquid crystals, and organic electronic materials requiring specific fluorinated aromatic components.
• Chemical Synthesis: Functions as a versatile reagent in organic synthesis for Friedel-Crafts acylation, esterification, and cross-coupling reactions to create complex polycyclic structures.
• Fluorine Chemistry Studies: Employed in academic and industrial R&D to study the effects of fluorine substitution on the physicochemical properties and reactivity of naphthalene-based compounds.

Basic Information

Item	Details
Product Name	Ethyl 6-Fluoro-4-Hydroxy-2-Naphthoate
CAS No.	1093073-40-5
Molecular Formula	C₁₃H₁₁FO₃
Molecular Weight	234.22 g/mol
Synonyms	6-Fluoro-4-hydroxy-2-naphthoic acid ethyl ester; Ethyl 6-fluoro-4-hydroxynaphthalene-2-carboxylate; 2-Naphthoic acid, 6-fluoro-4-hydroxy-, ethyl ester; 4-Hydroxy-6-fluoronaphthalene-2-carboxylic acid ethyl ester; 6-Fluoro-4-hydroxynaphthalene-2-carboxylic Acid Ethyl Ester; Ethyl 4-hydroxy-6-fluoronaphthalene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-Fluoro-4-Hydroxy-2-Naphthoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.