Description

(Betar)-β-Cyclopentyl-4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-1H-Pyrazole-1-Propanenitrile Sulfate is a high-purity, non-racemic chemical intermediate of significant interest in advanced pharmaceutical research. This compound matters for its role as a key building block in the synthesis of targeted kinase inhibitors, offering a critical structural motif for drug discovery programs. Pharmaceutical R&D teams and fine chemical manufacturers need this material to develop novel therapeutic agents, particularly in oncology and inflammatory disease research.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel kinase inhibitors for targeted cancer therapies.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and biological pathway studies.
• Drug Discovery & Development: Serves as a core scaffold for medicinal chemistry optimization and structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the final or penultimate steps of manufacturing complex, high-value active ingredients.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	(Betar)-β-Cyclopentyl-4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-1H-Pyrazole-1-Propanenitrile Sulfate
CAS No.	1092939-16-6
Molecular Formula	C17H19N7O4S
Molecular Weight	417.45 g/mol
Synonyms	4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1-(2-cyanoethyl)-1H-pyrazole-5-carboxylic acid, β-cyclopentyl ester, sulfate salt; (βR)-β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile sulfate; Betar-β-Cyclopentyl-4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-1H-Pyrazole-1-Propanenitrile Sulfate; Kinase Inhibitor Intermediate; Pyrrolopyrimidine-Pyrazole Derivative Sulfate
EINECS	Contact for details

Quality Control

Our (Betar)-β-Cyclopentyl-4-(7H-Pyrrolo[2,3-D]Pyrimidin-4-Yl)-1H-Pyrazole-1-Propanenitrile Sulfate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.