Description

6-(4-Fluorophenyl)-1,2-Dihydro-4-(1-Methylethyl)-2-Oxo-5-Pyrimidinecarbonitrile is a high-value, synthetically versatile pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a fluorophenyl group and a nitrile functionality, makes it an essential intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Serves as an intermediate in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure.
• Material Science: Potential building block for the synthesis of specialty chemicals, dyes, and functional materials requiring specific fluorinated aromatic systems.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	6-(4-Fluorophenyl)-1,2-Dihydro-4-(1-Methylethyl)-2-Oxo-5-Pyrimidinecarbonitrile
CAS No.	1092843-99-6
Molecular Formula	C14H12FN3O
Molecular Weight	257.26 g/mol
Synonyms	5-Cyano-6-(4-fluorophenyl)-4-isopropyl-1,2-dihydro-2-oxopyrimidine; 4-Isopropyl-6-(4-fluorophenyl)-2-oxo-1,2-dihydropyrimidine-5-carbonitrile; 6-(4-Fluorophenyl)-4-isopropyl-2-oxo-1,2-dihydro-5-pyrimidinecarbonitrile; 5-Pyrimidinecarbonitrile, 6-(4-fluorophenyl)-1,2-dihydro-4-(1-methylethyl)-2-oxo-; CAS 1092843-99-6
EINECS	Contact for details

Quality Control

Our 6-(4-Fluorophenyl)-1,2-Dihydro-4-(1-Methylethyl)-2-Oxo-5-Pyrimidinecarbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.