Description

4-Ethoxy-2,6-Difluorobenzylamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzylamine core with ethoxy and fluorine substituents. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its specific substitution pattern enables precise molecular modifications. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine moiety for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its aromatic and fluorine-containing structure.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs) serving the global life sciences market.

Basic Information

Product Name	4-Ethoxy-2,6-Difluorobenzylamine
CAS No.	1092461-39-6
Molecular Formula	C9H11F2NO
Molecular Weight	187.19 g/mol
Synonyms	2,6-Difluoro-4-ethoxybenzylamine; 1-(2,6-Difluoro-4-ethoxyphenyl)methanamine; 4-Ethoxy-2,6-difluorobenzenemethanamine; Benzenemethanamine, 2,6-difluoro-4-ethoxy-; (2,6-Difluoro-4-ethoxy-phenyl)-methylamine
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2,6-Difluorobenzylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.