Description

2-Methoxy-4,6-Bis(trifluoromethyl)aniline is a specialized fluorinated aniline derivative, serving as a high-value building block in advanced organic synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethyl groups and methoxy substituent, which are critical for modulating the reactivity and performance of final compounds. This compound is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used to construct advanced herbicide and pesticide molecules, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Functional Material Precursor: Employed in the research and development of organic electronic materials, such as semiconductors for OLEDs and OFETs.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing high-performance, light-fast dyes and pigments.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	2-Methoxy-4,6-Bis(trifluoromethyl)aniline
CAS No.	1092460-74-6
Molecular Formula	C10H7F6NO
Molecular Weight	271.16 g/mol
Synonyms	2-Methoxy-4,6-bis(trifluoromethyl)benzenamine; 4,6-Bis(trifluoromethyl)-2-methoxyaniline; 2-Amino-3-methoxy-1,5-bis(trifluoromethyl)benzene; 2-Methoxy-α,α,α,α',α',α'-hexafluoro-m-xylidine; Benzenamine, 2-methoxy-4,6-bis(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4,6-Bis(trifluoromethyl)aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.