Description

3,5-Difluoro-2-Methyl-Phenylamine is a high-purity fluorinated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which introduces both steric and electronic effects to modulate the properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro-methyl-phenylamine moiety can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic diamines and other monomers used in high-performance electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or chain modifier in the synthesis of specialty polymers, such as polyimides and polyamides, to improve thermal stability and solubility.
• Dye & Pigment Manufacturing: Employed in the synthesis of complex fluorinated dyes and pigments, offering improved lightfastness and color properties.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination, Suzuki coupling) for constructing complex biaryl systems.

Basic Information

Product Name	3,5-Difluoro-2-Methyl-Phenylamine
CAS No.	1092350-38-3
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	2-Methyl-3,5-difluoroaniline; 3,5-Difluoro-2-methylaniline; 2-Methyl-3,5-difluorobenzenamine; 3,5-Difluoro-o-toluidine; Benzenamine, 3,5-difluoro-2-methyl-; (3,5-Difluoro-2-methylphenyl)amine
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-2-Methyl-Phenylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents. For long-term storage, consider using an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.