Description

2-Chloro-6-Fluorobenzyl Isothiocyanate is a versatile and highly reactive organic building block characterized by its unique combination of halogen and isothiocyanate functional groups. This compound is critical for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research where precise structural modifications are required. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its reactive site for structural diversification.
• Chemical Biology Probe: Serves as a valuable tool compound for labeling and studying biological targets due to the electrophilic nature of the isothiocyanate group.
• Material Science Research: Employed in the creation of specialized polymers or functional materials that require halogenated aromatic backbones.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2-Chloro-6-Fluorobenzyl Isothiocyanate
CAS No.	1092350-26-9
Molecular Formula	C8H5ClFNS
Molecular Weight	201.65 g/mol
Synonyms	1-(Chloro-6-fluorophenyl)methyl Isothiocyanate; (2-Chloro-6-fluorophenyl)methyl Isothiocyanate; 2-Chloro-6-fluorobenzyl Isothiocyanate; 2-Chloro-6-fluoro-α-isothiocyanatotoluene; Benzene, 1-(chloro-6-fluoro)-, (isothiocyanatomethyl)-; Isothiocyanic Acid, (2-Chloro-6-fluorobenzyl) Ester
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-Fluorobenzyl Isothiocyanate is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.