Description

4-(3,4-Dimethoxyphenyl)Pyrimidine-2(1H)-Thione is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role as a versatile precursor in the development of novel active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its bioactive pyrimidine-thione core.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing more complex heterocyclic compounds through various coupling and cyclization reactions.
• Material Science: Investigated as a monomer or ligand for creating functional polymers, coordination complexes, and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for biological target identification.

Basic Information

Product Name	4-(3,4-Dimethoxyphenyl)Pyrimidine-2(1H)-Thione
CAS No.	1092303-07-5
Molecular Formula	C₁₂H₁₂N₂O₂S
Molecular Weight	248.30 g/mol
Synonyms	4-(3,4-Dimethoxyphenyl)-2-mercaptopyrimidine; 4-(3,4-Dimethoxyphenyl)-2-pyrimidinethiol; 4-(3,4-Dimethoxyphenyl)-1H-pyrimidine-2-thione; 2-Mercapto-4-(3,4-dimethoxyphenyl)pyrimidine; 2-Thioxo-1,2-dihydro-4-(3,4-dimethoxyphenyl)pyrimidine; 4-Veratryl-2-pyrimidinethiol; 4-(3,4-Dimethoxyphenyl)-2-thioxo-1,2-dihydropyrimidine
EINECS	Contact for details

Quality Control

Our 4-(3,4-Dimethoxyphenyl)Pyrimidine-2(1H)-Thione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.