Description

4-(Trifluoromethyl)Pyrimidin-5-Amine is a high-value pyrimidine derivative featuring a reactive amine group and a stable trifluoromethyl substituent. This compound is a critical building block in modern synthetic chemistry, prized for its ability to impart desirable physicochemical properties to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and kinase inhibitor research programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized heterocyclic compounds used in organic electronics, liquid crystals, and advanced polymer systems.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring high-purity, specialized heterocyclic amines.

Basic Information

Product Name	4-(Trifluoromethyl)Pyrimidin-5-Amine
CAS No.	1092299-22-3
Molecular Formula	C5H4F3N3
Molecular Weight	163.10 g/mol
Synonyms	5-Amino-4-(trifluoromethyl)pyrimidine; 4-(Trifluoromethyl)-5-pyrimidinamine; 5-Pyrimidinamine, 4-(trifluoromethyl)-; 4-Trifluoromethylpyrimidin-5-ylamine; 4-CF3-Pyrimidin-5-amine
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethyl)Pyrimidin-5-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.