Description

4-(Azocan-1-Yl)-3-Fluoroaniline is a specialized fluorinated aniline derivative featuring an eight-membered azocane ring, making it a valuable building block in advanced organic synthesis. This compound is engineered to introduce both fluorine and a constrained cyclic amine moiety into target molecules, which can significantly alter their physicochemical and biological properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, where the fluorine atom can enhance metabolic stability and membrane permeability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity-modifying effects of the fluorine substituent and the azocane scaffold.
• Material Science: Acts as a monomer or functionalizing agent in the production of specialty polymers, dyes, and liquid crystals, where its structure can impart unique electronic or self-assembly properties.
• Chemical Biology Probe Development: Employed as a scaffold for creating fluorescent tags, enzyme inhibitors, or other molecular probes used in biochemical and cellular research.
• Organic Synthesis Building Block: Provides a versatile handle for further functionalization via reactions at the aniline nitrogen or the aromatic ring, enabling the construction of complex molecular architectures.

Basic Information

Product Name	4-(Azocan-1-Yl)-3-Fluoroaniline
CAS No.	1092279-99-6
Molecular Formula	C14H21FN2
Molecular Weight	236.33 g/mol
Synonyms	3-Fluoro-4-(azocan-1-yl)aniline; 1-(5-Amino-2-fluorophenyl)azocane; 4-(Azepan-1-yl)-3-fluoroaniline (common misnomer for the 8-membered ring); 3-Fluoro-4-(octahydroazocin-1-yl)aniline; Benzenamine, 3-fluoro-4-(azocan-1-yl)-; FQA (Fluoro Quaternary Amine building block); Azocane-1-yl-fluoroaniline derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 4-(Azocan-1-Yl)-3-Fluoroaniline is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS is supplied with each shipment. Our quality commitment supports compliance with ISO 9001 guidelines and customer-specific regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.