Description

5-(3-(2-Chloropyrimidin-4-Yl)Imidazo[1,2-A]Pyridin-2-Yl)-n-(2,6-Difluorophenyl)-2-Methoxybenzamide is a sophisticated heterocyclic organic compound that serves as a critical building block in modern pharmaceutical research and development. Its complex molecular architecture, featuring fused imidazopyridine and pyrimidine rings, makes it a valuable intermediate for creating targeted therapeutic agents. This high-purity compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel small-molecule drug candidates, particularly in oncology and kinase inhibitor research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Biochemical Probe Development: Utilized in the design and synthesis of chemical probes for studying specific biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for global clients.
• Academic Research: Employed in university and institutional labs for cutting-edge research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	5-(3-(2-Chloropyrimidin-4-Yl)Imidazo[1,2-A]Pyridin-2-Yl)-n-(2,6-Difluorophenyl)-2-Methoxybenzamide
CAS No.	1089278-50-1
Molecular Formula	C25H16ClF2N5O2
Molecular Weight	483.88 g/mol
Synonyms	5-[3-(2-Chloropyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-methoxybenzamide; 1089278-50-1; UNII-9J2V6U6E8I; 9J2V6U6E8I; Benzamide, 5-[3-(2-chloro-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-methoxy-; AKOS025310999; CS-0476225
EINECS	Contact for details

Quality Control

Our production of 5-(3-(2-Chloropyrimidin-4-Yl)Imidazo[1,2-A]Pyridin-2-Yl)-n-(2,6-Difluorophenyl)-2-Methoxybenzamide adheres to stringent quality protocols suitable for pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.