Description

1-(2-Bromo-4-Fluorophenyl)Ethanamine is a high-purity, halogenated aromatic amine building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo- and fluoro-substituted motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the bromo-fluorophenyl group can enhance biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of monomers for advanced polymers, liquid crystals, or organic electronic materials requiring halogenated aromatic units.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(2-Bromo-4-Fluorophenyl)Ethanamine
CAS No.	1086599-35-0
Molecular Formula	C8H9BrFN
Molecular Weight	218.07 g/mol
Synonyms	α-Methyl-2-bromo-4-fluoroaniline; 1-(2-Bromo-4-fluorophenyl)ethan-1-amine; 2-Bromo-4-fluoro-α-methylbenzylamine; 1-Aminoethyl-2-bromo-4-fluorobenzene; (2-Bromo-4-fluorophenyl)ethanamine; 2-Bromo-4-fluoro-α-methylbenzenemethanamine; 1-(2-Bromo-4-fluorophenyl)ethylamine
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-4-Fluorophenyl)Ethanamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH Q7, and other relevant regulatory guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.