Description

1-(3-Methoxypropyl)-4-Oxo-1,4-Dihydropyrido[1,2-A]Pyrrolo[2,3-D]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers focused on developing new therapeutic agents, especially in oncology and other targeted therapy areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the design of novel kinase inhibitors or other targeted small molecules.
• Preclinical Drug Development: Used in the production of compounds for pharmacological screening, toxicology studies, and formulation development.
• Contract Manufacturing: Supplied to CMOs for scale-up synthesis under cGMP conditions for clinical trial material production.
• Academic Research: Utilized in university and institutional labs for chemical biology studies and the development of new synthetic methodologies.
• Bioconjugation Chemistry: The carboxylic acid moiety allows for further derivatization and conjugation to linkers, peptides, or other functional groups.

Basic Information

Item	Details
Product Name	1-(3-Methoxypropyl)-4-Oxo-1,4-Dihydropyrido[1,2-A]Pyrrolo[2,3-D]Pyrimidine-2-Carboxylic Acid
CAS No.	1086386-77-7
Molecular Formula	C16H15N3O4
Molecular Weight	313.31 g/mol
Synonyms	1-(3-Methoxypropyl)-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxylic acid; Pyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxylic acid, 1,4-dihydro-1-(3-methoxypropyl)-4-oxo-; 1086386-77-7; UNII-9Q8W7U7Q8F; 9Q8W7U7Q8F; 1-(3-Methoxypropyl)-4-oxo-1H,4H-pyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(3-Methoxypropyl)-4-Oxo-1,4-Dihydropyrido[1,2-A]Pyrrolo[2,3-D]Pyrimidine-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to support regulatory filings for preclinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.