Description

6-Chloro-n-(4-Pyridinylmethyl)-4-Pyrimidinamine is a high-purity organic compound belonging to the pyrimidine class, characterized by its distinct chloro and pyridinylmethyl substituents. This compound serves as a critical pharmaceutical intermediate and research chemical in the development of novel therapeutic agents. It is primarily utilized by R&D laboratories and manufacturing facilities in the pharmaceutical and biotechnology sectors for drug discovery and process chemistry applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Kinase Inhibitor Research: Used in the research and development of small molecule inhibitors for kinases, a prominent target class in oncology and inflammatory diseases.
• Chemical Biology Probe: Serves as a scaffold or precursor for creating probes to study biological processes and protein functions.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug development pipelines.

Basic Information

Item	Detail
Product Name	6-Chloro-n-(4-Pyridinylmethyl)-4-Pyrimidinamine
CAS No.	1086386-59-5
Molecular Formula	C10H9ClN4
Molecular Weight	220.66 g/mol
Synonyms	6-Chloro-N-[(pyridin-4-yl)methyl]pyrimidin-4-amine; 6-Chloro-N-(pyridin-4-ylmethyl)pyrimidin-4-amine; 4-Pyrimidinamine, 6-chloro-N-(4-pyridinylmethyl)-; 6-Chloro-N-(4-pyridylmethyl)pyrimidin-4-amine; 1086386-59-5; 6-Chloro-N-(4-pyridinylmethyl)-4-pyrimidinamine; 6-Chloro-N-(4-pyridylmethyl)-4-pyrimidinamine; 6-Chloro-N-(4-pyridinylmethyl)pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 6-Chloro-n-(4-Pyridinylmethyl)-4-Pyrimidinamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.