Description

Methyl 7-Isobutyl-1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate, 96% is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted kinase inhibitors and other biologically active molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies during drug discovery programs.
• API Synthesis: Serves as a core scaffold for constructing final active pharmaceutical ingredients with specific receptor binding profiles.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Biochemical Research: Employed as a tool compound to study enzyme inhibition mechanisms and cellular signaling pathways.
• Academic Research: Utilized in university and institutional labs for the development of new synthetic methodologies involving fused heterocyclic systems.

Basic Information

Item	Details
Product Name	Methyl 7-Isobutyl-1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate, 96%
CAS No.	1086386-40-4
Molecular Formula	C15H21N3O4
Molecular Weight	307.35 g/mol
Synonyms	Methyl 7-isobutyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate; 6-Carbomethoxy-7-isobutyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 7-(2-methylpropyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-, methyl ester; CAS 1086386-40-4
EINECS	Contact for details

Quality Control

Our Methyl 7-Isobutyl-1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate, 96% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the specified 96% minimum purity and is suitable for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect the material from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.