Description

Methyl 7-(3-Methoxypropyl)-1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate, 96% is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting kinase inhibition. It is essential for research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, where consistent quality and reliable supply are paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• API Synthesis: Used in the construction of the core scaffold for purine-analogue based drug candidates.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Can be utilized in the development of assay probes to study specific enzymatic pathways and cellular processes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.

Basic Information

Product Name	Methyl 7-(3-Methoxypropyl)-1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate, 96%
CAS No.	1086386-38-0
Molecular Formula	C14H19N3O5
Molecular Weight	309.32 g/mol
Synonyms	Methyl 7-(3-methoxypropyl)-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-6H-pyrrolo[2,3-d]pyrimidine-6-carboxylate; 6H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 1,2,3,4-tetrahydro-7-(3-methoxypropyl)-1,3-dimethyl-2,4-dioxo-, methyl ester; 1086386-38-0; Pyrrolo[2,3-d]pyrimidine derivative; Kinase inhibitor intermediate
EINECS	Contact for details

Quality Control

Our Methyl 7-(3-Methoxypropyl)-1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate, 96% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and pre-clinical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 96.0%
Related Substances (HPLC)	Total impurities ≤ 4.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.