Description

7-Benzyl-1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the generation of compound libraries for high-throughput screening.
• API Development: Used in the process development and scale-up stages for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme function and cellular pathways in academic and industrial R&D settings.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific molecular framework.

Basic Information

Product Name	7-Benzyl-1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid
CAS No.	1086386-28-8
Molecular Formula	C₁₇H₁₅N₃O₄
Molecular Weight	325.32 g/mol
Synonyms	7-Benzyl-1,3-dimethyl-2,4-dioxo-2,3,4,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid; 1H-Pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, 2,3,4,7-tetrahydro-7-benzyl-1,3-dimethyl-2,4-dioxo-; 1086386-28-8; 7-Benzyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our 7-Benzyl-1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent specifications required for pharmaceutical R&D and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.