Description

4-Bromo-6-(3-Tolyl)Pyrimidine is a high-purity halogenated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the development of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging the pyrimidine core's bioactivity.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology Probe Development: Employed to create tagged or modified molecules for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Library Synthesis for High-Throughput Screening: Used in combinatorial chemistry to generate diverse compound libraries for biological activity screening.

Basic Information

Product Name	4-Bromo-6-(3-Tolyl)Pyrimidine
CAS No.	1086382-23-1
Molecular Formula	C11H9BrN2
Molecular Weight	249.11 g/mol
Synonyms	4-Bromo-6-(m-tolyl)pyrimidine; 6-(3-Methylphenyl)-4-bromopyrimidine; 4-Bromo-6-(3-methylphenyl)pyrimidine; 4-Bromo-6-m-tolylpyrimidine; 1086382-23-1; 4-Br-6-(3-Me-Ph)-Pyrimidine
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-6-(3-Tolyl)Pyrimidine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.