Description

4-Bromo-6-Cyclopropylpyrimidine is a high-value halogenated pyrimidine building block, essential for advanced organic synthesis and pharmaceutical research. Its core value lies in providing a versatile scaffold for constructing complex molecules, enabling the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the biological activity of the pyrimidine core.
• Material Science: Serves as a precursor for creating functionalized organic materials and ligands for metal-organic frameworks (MOFs) or catalysts.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Chemical Biology: Used as a probe or labeling agent in biochemical research due to its reactive halogen site.
• Custom Synthesis: A fundamental building block for contract research organizations (CROs) and custom synthesis manufacturers to produce client-specific target molecules.

Basic Information

Product Name	4-Bromo-6-Cyclopropylpyrimidine
CAS No.	1086382-13-9
Molecular Formula	C7H7BrN2
Molecular Weight	199.05 g/mol
Synonyms	6-Cyclopropyl-4-bromopyrimidine; 4-Bromo-6-cyclopropyl-pyrimidine; Pyrimidine, 4-bromo-6-cyclopropyl-; 1086382-13-9; 4-Bromo-6-cyclopropyl pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Bromo-6-Cyclopropylpyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.