Description

4-[(2-Chloropyrimidin-4-Yl)Oxy]Benzaldehyde CAS NO 1086378-89-3 is a high-purity, advanced pharmaceutical intermediate characterized by its benzaldehyde core functionalized with a chloropyrimidinyloxy moiety. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides and fungicides due to its bioactive heterocyclic structure.
• Material Science: Serves as a monomer or cross-linking agent in the creation of specialty polymers with specific electronic or optical properties.
• Academic & Contract Research: Employed in organic synthesis laboratories for method development and structure-activity relationship (SAR) studies.
• Bioconjugation Chemistry: The aldehyde group allows for site-specific conjugation to proteins, antibodies, or other biomolecules for diagnostic or therapeutic applications.

Basic Information

Product Name	4-[(2-Chloropyrimidin-4-Yl)Oxy]Benzaldehyde
CAS No.	1086378-89-3
Molecular Formula	C11H7ClN2O2
Molecular Weight	234.64 g/mol
Synonyms	4-[(2-Chloro-4-pyrimidinyl)oxy]benzaldehyde; 4-(2-Chloropyrimidin-4-yloxy)benzaldehyde; Benzaldehyde, 4-[(2-chloro-4-pyrimidinyl)oxy]-; 2-Chloro-4-(4-formylphenoxy)pyrimidine; 4-(2-Chloro-pyrimidin-4-yloxy)-benzaldehyde; p-[(2-Chloropyrimidin-4-yl)oxy]benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-[(2-Chloropyrimidin-4-Yl)Oxy]Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.