Description

2-Fluoro-5-[1,2,4]Triazol-4-Yl-Phenylamine is a high-purity heterocyclic aromatic amine building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, combining a fluorinated phenyl ring with a [1,2,4]triazole moiety, making it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in areas like kinase inhibitors, antiviral agents, and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine and triazole groups contribute to biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components, due to its conjugated system.
• Chemical Biology Probes: Useful for designing molecular probes and tags to study biological processes and protein interactions.
• Custom Synthesis and Scale-Up: Supplied for contract research organizations (CROs) and contract development and manufacturing organizations (CDMOs) requiring reliable, high-quality building blocks for custom synthesis projects.

Basic Information

Product Name	2-Fluoro-5-[1,2,4]Triazol-4-Yl-Phenylamine
CAS No.	1082766-13-9
Molecular Formula	C8H6FN5
Molecular Weight	191.17 g/mol
Synonyms	4-(4-Amino-2-fluorophenyl)-1,2,4-triazole; 2-Fluoro-5-(1H-1,2,4-triazol-1-yl)aniline; 2-Fluoro-5-(1,2,4-triazol-1-yl)aniline; 1-(4-Amino-2-fluorophenyl)-1H-1,2,4-triazole; 1082766-13-9; 2-Fluoro-5-(1,2,4-triazol-1-yl)benzenamine; Aniline, 2-fluoro-5-(1H-1,2,4-triazol-1-yl)-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-[1,2,4]Triazol-4-Yl-Phenylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.