Description

6-(1-Benzyl-4-Methylpyrrolidin-3-Yl)-1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4(5H)-One is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound is valued for its complex heterocyclic structure, which serves as a key building block in the synthesis of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Kinase Inhibitor Research: Serves as a core scaffold for the development and optimization of novel kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies to explore new chemical entities and improve pharmacological profiles.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological mechanisms and validate new therapeutic targets.
• Custom Synthesis Building Block: Provided to contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.

Basic Information

Product Name	6-(1-Benzyl-4-Methylpyrrolidin-3-Yl)-1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4(5H)-One
CAS No.	1082743-69-8
Molecular Formula	C23H29N5O2
Molecular Weight	407.51 g/mol
Synonyms	6-(1-Benzyl-4-methyl-3-pyrrolidinyl)-1-(tetrahydro-2H-pyran-4-yl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; 1H-Pyrazolo[3,4-d]pyrimidin-4(5H)-one, 6-(1-benzyl-4-methyl-3-pyrrolidinyl)-1-(tetrahydro-2H-pyran-4-yl)-; 1082743-69-8; BMT-PP Inhibitor Intermediate; Kinase Scaffold 1082743
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.