Description

3-(3-Methylphenyl)-3,6-Dihydro-7H-[1,2,3]Triazolo[4,5-D]Pyrimidin-7-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic compound class. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research and development. It is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted kinase inhibitors and other small molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Process Chemistry & Scale-Up: Serves as a defined intermediate for process route development and cGMP manufacturing of clinical trial materials.
• Biochemical Tool Compound: Potential use in biochemical assays for target validation and screening in drug discovery programs.
• Academic Research: Employed in university and institutional labs for heterocyclic chemistry studies and novel synthetic methodology development.

Basic Information

Product Name	3-(3-Methylphenyl)-3,6-Dihydro-7H-[1,2,3]Triazolo[4,5-D]Pyrimidin-7-One
CAS No.	1082436-86-9
Molecular Formula	C12H10N6O
Molecular Weight	254.25 g/mol
Synonyms	3-(3-Methylphenyl)-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one; 7H-[1,2,3]Triazolo[4,5-d]pyrimidin-7-one, 3,6-dihydro-3-(3-methylphenyl)-; 3-(m-Tolyl)-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one; CAS 1082436-86-9; Triazolopyrimidinone derivative; m-Tolyl-triazolopyrimidinone
EINECS	Contact for details

Quality Control

Our production of 3-(3-Methylphenyl)-3,6-Dihydro-7H-[1,2,3]Triazolo[4,5-D]Pyrimidin-7-One adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is fully characterized and undergoes rigorous analytical testing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.