Description

2-(2-Methyl-1H-Indol-3-Yl)-n-[3-(Methylsulfanyl)-1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Propyl]Acetamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold for targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates in preclinical and clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for potential therapeutic use.
• Biochemical Research: Potential tool compound for investigating enzyme inhibition or receptor modulation in biological assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and drug discovery programs.

Basic Information

Product Name	2-(2-Methyl-1H-Indol-3-Yl)-n-[3-(Methylsulfanyl)-1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Propyl]Acetamide
CAS No.	1081133-52-9
Molecular Formula	C21H23N5OS
Molecular Weight	401.51 g/mol
Synonyms	2-(2-Methyl-1H-indol-3-yl)-N-[3-(methylsulfanyl)-1-([1,2,4]triazolo[4,3-a]pyridin-3-yl)propyl]acetamide; 1081133-52-9; UNII-8Q2VQK8Q4W; 8Q2VQK8Q4W; CHEMBL3186660; BDBM50166631; AKOS025147424; ZINC000003869007
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Methyl-1H-Indol-3-Yl)-n-[3-(Methylsulfanyl)-1-([1,2,4]Triazolo[4,3-A]Pyridin-3-Yl)Propyl]Acetamide is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for use under cGMP (current Good Manufacturing Practice) guidelines for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.