Description

n-(3-Methoxyphenyl)-1-Methyl-4-(Pyrrolidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest due to its role as a key building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is primarily required by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the development of novel drug candidates for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent and selective kinase inhibitors for cancer research.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic assays and structure-activity relationship (SAR) studies.
• Medicinal Chemistry: Serves as a core scaffold for the design and development of new chemical entities (NCEs) targeting specific biological pathways.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	n-(3-Methoxyphenyl)-1-Methyl-4-(Pyrrolidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Amine
CAS No.	1081122-05-5
Molecular Formula	C17H20N6O
Molecular Weight	324.38 g/mol
Synonyms	6-[(3-Methoxyphenyl)amino]-1-methyl-4-(1-pyrrolidinyl)-1H-pyrazolo[3,4-d]pyrimidine; 1-Methyl-4-(pyrrolidin-1-yl)-N-(3-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine; UNII-9W6H8V3A4S; 1081122-05-5; 1H-Pyrazolo[3,4-d]pyrimidin-6-amine, N-(3-methoxyphenyl)-1-methyl-4-(1-pyrrolidinyl)-; 9W6H8V3A4S
EINECS	Contact for details

Quality Control

Our production of n-(3-Methoxyphenyl)-1-Methyl-4-(Pyrrolidin-1-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-6-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, typically determined by advanced analytical techniques including HPLC, NMR, and mass spectrometry. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.