Description

(1R)-1-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Ethylamine is a high-value chiral amine building block characterized by its fluorinated aromatic ring system. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its specific stereochemistry and fluorine atoms impart desirable metabolic stability and binding affinity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine groups enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with unique electronic properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(1R)-1-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Ethylamine
CAS No.	1079656-93-1
Molecular Formula	C9H7F4N
Molecular Weight	205.15 g/mol
Synonyms	(1R)-1-(2-Fluoro-3-(trifluoromethyl)phenyl)ethan-1-amine; (R)-1-(2-Fluoro-3-(trifluoromethyl)phenyl)ethylamine; (R)-α-Methyl-2-fluoro-3-(trifluoromethyl)benzylamine; (R)-1-[2-Fluoro-3-(trifluoromethyl)phenyl]ethanamine; 1079656-93-1; (R)-2-Fluoro-α-methyl-3-(trifluoromethyl)benzylamine
EINECS	Contact for details

Quality Control

Our (1R)-1-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and enantiomeric excess is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.