Description

(1R)-1-[2-Fluoro-5-(Trifluoromethyl)Phenyl]Ethylamine is a high-purity chiral amine building block of significant importance in advanced organic synthesis. Its value lies in its unique molecular architecture, featuring a trifluoromethyl group and a fluorine atom on the aromatic ring, which are critical for modulating the physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients where stereochemistry and fluorination are key design elements.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored electronic or surface properties.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study biological processes and enzyme mechanisms.

Basic Information

Product Name	(1R)-1-[2-Fluoro-5-(Trifluoromethyl)Phenyl]Ethylamine
CAS No.	1079656-78-2
Molecular Formula	C9H9F4N
Molecular Weight	207.17 g/mol
Synonyms	(1R)-1-(2-Fluoro-5-(trifluoromethyl)phenyl)ethanamine; (R)-1-[2-Fluoro-5-(trifluoromethyl)phenyl]ethylamine; (R)-α-Methyl-2-fluoro-5-(trifluoromethyl)benzylamine; (R)-1-(2-Fluoro-α-methylbenzyl)-4-(trifluoromethyl)benzene; Benzenemethanamine, α-methyl-2-fluoro-5-(trifluoromethyl)-, (alphaR)-; (R)-2-Fluoro-α-methyl-5-(trifluoromethyl)benzylamine
EINECS	Contact for details

Quality Control

Our (1R)-1-[2-Fluoro-5-(Trifluoromethyl)Phenyl]Ethylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.