Description

D-γ-Glu(Ome)-Lys(Tfa)-D-Ala-D-Ala-Ome is a specialized, high-purity peptide derivative designed for advanced research and pharmaceutical development. This compound serves as a critical building block or intermediate in the synthesis of complex peptidomimetics and novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on antibiotic research, enzyme inhibitor studies, and peptide-based drug discovery. Its precise structure allows for targeted modifications in the development of new bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel antibiotic candidates and antimicrobial peptides.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving bacterial cell wall synthesis pathways.
• Peptidomimetic Development: Serves as a core structure for designing and synthesizing stable peptide analogs with enhanced pharmacological properties.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of peptide-based therapeutics.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in peptide analysis.

Basic Information

Item	Detail
Product Name	D-γ-Glu(Ome)-Lys(Tfa)-D-Ala-D-Ala-Ome
CAS No.	1078203-19-6
Molecular Formula	C24H39N5O11
Molecular Weight	573.60 g/mol
Synonyms	H-D-γ-Glu(OMe)-Lys(Tfa)-D-Ala-D-Ala-OMe; (2R)-2-[[(2R)-2-[[(4S)-4-[[(2R)-5-Methoxy-5-oxo-2-[[(2R)-2-(trifluoroacetamido)-6-(trifluoroacetamido)hexanoyl]amino]pentanoyl]amino]-5-(trifluoroacetamido)pentanoyl]amino]propanoyl]amino]propanoic acid methyl ester; D-γ-Glu(OMe)-Lys(Tfa)-D-Ala-D-Ala-OMe; Boc-D-γ-Glu(OMe)-Lys(Tfa)-D-Ala-D-Ala-OMe (protected form); Nα-(Tfa)-Lys-D-γ-Glu(OMe)-D-Ala-D-Ala-OMe
EINECS	Contact for details

Quality Control

Every batch of D-γ-Glu(Ome)-Lys(Tfa)-D-Ala-D-Ala-Ome is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocol is designed to meet the stringent requirements of pharmaceutical R&D and includes testing by HPLC, MS, and NMR. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.