Description

tert-Butyl 2-[4-(2-Fluorophenyl)-6-Methylthieno[2,3-D]Pyrimidin-2-Ylamino]Acetate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key building block for creating novel therapeutic agents. It is primarily utilized by pharmaceutical manufacturers and R&D laboratories focused on developing new drug candidates, particularly in oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of active pharmaceutical ingredients (APIs) for clinical research and commercial manufacturing.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates targeting specific biological pathways.
• Oncology Drug Development: Used in the synthesis of potential kinase inhibitors and other targeted cancer therapies due to its thienopyrimidine core structure.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale synthesis to establish robust and cost-effective manufacturing processes.

Basic Information

Product Name	tert-Butyl 2-[4-(2-Fluorophenyl)-6-Methylthieno[2,3-D]Pyrimidin-2-Ylamino]Acetate
CAS No.	1076199-69-3
Molecular Formula	C19H20FN3O2S
Molecular Weight	373.45 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)methylamino]-4-(2-fluorophenyl)-6-methylthieno[2,3-d]pyrimidine; tert-Butyl N-[2-[4-(2-fluorophenyl)-6-methylthieno[2,3-d]pyrimidin-2-yl]amino]acetate; 1076199-69-3; 2-((tert-Butoxycarbonyl)methylamino)-4-(2-fluorophenyl)-6-methylthieno[2,3-d]pyrimidine; BOC-protected thienopyrimidine amine derivative
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-[4-(2-Fluorophenyl)-6-Methylthieno[2,3-D]Pyrimidin-2-Ylamino]Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical R&D. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area %)	≥98.0%
Single Maximum Impurity	≤1.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.