Description

(2-Amino-5,6,7,8-Tetrahydro-Quinazolin-6-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development, particularly for candidates targeting central nervous system and oncological pathways.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the development and scale-up of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical studies.
• Drug Discovery Research: Serves as a versatile scaffold in combinatorial chemistry and high-throughput screening libraries for identifying new biological activities.
• Process Chemistry Development: Employed in route scouting and optimization studies to establish robust, scalable manufacturing processes for new chemical entities.
• Chemical Biology Probes: Can be utilized to create specialized molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(2-Amino-5,6,7,8-Tetrahydro-Quinazolin-6-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1073633-86-9
Molecular Formula	C₁₃H₂₀N₄O₂
Molecular Weight	264.33 g/mol
Synonyms	tert-Butyl N-(2-amino-5,6,7,8-tetrahydroquinazolin-6-yl)carbamate; 6-[(tert-Butoxycarbonyl)amino]-5,6,7,8-tetrahydroquinazolin-2-amine; BOC-6-ATQ; N-Boc-2-Amino-5,6,7,8-tetrahydroquinazolin-6-amine; (2-Amino-5,6,7,8-tetrahydroquinazolin-6-yl)carbamic acid tert-butyl ester; 6-(Boc-amino)-5,6,7,8-tetrahydro-2-quinazolinamine; 1073633-86-9
EINECS	Contact for details

Quality Control

Our (2-Amino-5,6,7,8-Tetrahydro-Quinazolin-6-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.