Description

tert-Butyl 4-Hydroxy-2-Methyl-5H,6H,7H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, serving as a key building block for the synthesis of novel, biologically active molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of targeted kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Process Chemistry Development: Serves as a standard or starting material for scaling up and optimizing synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Tool Compound: Can be utilized in biochemical assays to study enzyme function and inhibition mechanisms.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Item	Details
Product Name	tert-Butyl 4-Hydroxy-2-Methyl-5H,6H,7H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylate
CAS No.	1073477-40-3
Molecular Formula	C12H17N3O3
Molecular Weight	251.28 g/mol
Synonyms	4-Hydroxy-2-methyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester; 6-(tert-Butoxycarbonyl)-4-hydroxy-2-methyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine; tert-Butyl 4-hydroxy-2-methyl-5,8-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylate; 4-Hydroxy-2-methyl-5,6,7,8-tetrahydropyrrolo[3,4-d]pyrimidine-6-carboxylic acid 1,1-dimethylethyl ester; Pyrrolo[3,4-d]pyrimidine-6-carboxylic acid, 5,6,7,8-tetrahydro-4-hydroxy-2-methyl-, 1,1-dimethylethyl ester; CAS 1073477-40-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Hydroxy-2-Methyl-5H,6H,7H-Pyrrolo[3,4-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.