Description

2-Methyl-4-Oxo-3,5,7,8-Tetrahydro-4H-Pyrido[4,3-D]Pyrimidine-6-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key synthetic building block for creating novel, complex molecules with targeted therapeutic effects. It is primarily required by research institutions and pharmaceutical companies engaged in the synthesis of new chemical entities, particularly for applications in oncology and central nervous system (CNS) drug development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Kinase Inhibitor Synthesis: Serves as a core scaffold in the development of novel kinase inhibitors for targeted cancer therapies.
• CNS-Active Compound Development: Employed in the research and synthesis of potential therapeutics for neurological disorders.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Industrial R&D: Utilized in university and corporate laboratories for exploratory organic synthesis and new methodology development.

Basic Information

Product Name	2-Methyl-4-Oxo-3,5,7,8-Tetrahydro-4H-Pyrido[4,3-D]Pyrimidine-6-Carboxylic Acid tert-Butyl Ester
CAS No.	1073440-84-2
Molecular Formula	C14H19N3O3
Molecular Weight	277.32 g/mol
Synonyms	tert-Butyl 2-methyl-4-oxo-3,5,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidine-6-carboxylate; 4H-Pyrido[4,3-d]pyrimidine-6-carboxylic acid, 3,5,7,8-tetrahydro-2-methyl-4-oxo-, 1,1-dimethylethyl ester; 2-Methyl-4-oxo-3,4,5,7,8-pentahydropyrido[4,3-d]pyrimidine-6-carboxylic acid tert-butyl ester; Pyrido[4,3-d]pyrimidine derivative; BOC-protected pyridopyrimidine intermediate
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-Oxo-3,5,7,8-Tetrahydro-4H-Pyrido[4,3-D]Pyrimidine-6-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.