Description

3-Iodo-5-(Trifluoromethyl)Phenol is a high-value halogenated phenol derivative, distinguished by its unique trifluoromethyl and iodine substituents. This compound is a critical advanced pharmaceutical intermediate and versatile building block for synthesizing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to introduce specific functional groups and modulate the physicochemical properties of target compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting novel therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as a reliable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) due to the reactive iodine moiety.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for imaging and diagnostic applications.

Basic Information

Product Name	3-Iodo-5-(Trifluoromethyl)Phenol
CAS No.	1073339-06-6
Molecular Formula	C7H4F3IO
Molecular Weight	287.01 g/mol
Synonyms	5-(Trifluoromethyl)-3-iodophenol; 3-Iodo-α,α,α-trifluoro-m-cresol; 3-Iodo-5-(trifluoromethyl)benzenol; Phenol, 3-iodo-5-(trifluoromethyl)-; m-Iodo-α,α,α-trifluorocresol
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-(Trifluoromethyl)Phenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.