Description

4-(4-Chloro-5-(Trifluoromethyl)Pyrimidin-2-Ylamino)-n-Methylbenzamide is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. Its core value lies in its role as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the biological activity of the pyrimidine core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds.
• Material Science Research: Potential building block for organic electronic materials or metal-organic frameworks (MOFs) due to its aromatic and heterocyclic structure.

Basic Information

Product Name	4-(4-Chloro-5-(Trifluoromethyl)Pyrimidin-2-Ylamino)-n-Methylbenzamide
CAS No.	1073160-19-6
Molecular Formula	C13H9ClF3N4O
Molecular Weight	329.69 g/mol
Synonyms	4-[(4-Chloro-5-(trifluoromethyl)-2-pyrimidinyl)amino]-N-methylbenzamide; N-Methyl-4-((4-chloro-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide; 4-((4-Chloro-5-(trifluoromethyl)pyrimidin-2-yl)amino)-N-methylbenzamide; CAS 1073160-19-6; 4-(4-Chloro-5-trifluoromethyl-pyrimidin-2-ylamino)-N-methyl-benzamide
EINECS	Contact for details

Quality Control

Our 4-(4-Chloro-5-(Trifluoromethyl)Pyrimidin-2-Ylamino)-n-Methylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.