Description

Methyl 4-Cyclopropyl-2-Morpholinopyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined molecular architecture. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of potential drug candidates targeting various disease pathways.
• Kinase Inhibitor Development: Used in the construction of heterocyclic cores for molecules designed as kinase inhibitors, a major class in oncology and anti-inflammatory therapeutics.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes due to its morpholino and cyclopropyl functional groups.
• Chemical Biology Probes: Acts as a starting material for creating specialized probes used to study biological mechanisms and enzyme functions.
• Custom Synthesis: Supplied for bespoke organic synthesis projects requiring this specific pyrimidine derivative.

Basic Information

Product Name	Methyl 4-Cyclopropyl-2-Morpholinopyrimidine-5-Carboxylate
CAS No.	1072944-54-7
Molecular Formula	C13H17N3O3
Molecular Weight	263.29 g/mol
Synonyms	Methyl 4-cyclopropyl-2-(morpholin-4-yl)pyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 4-cyclopropyl-2-(4-morpholinyl)-, methyl ester; 4-Cyclopropyl-2-morpholin-4-yl-pyrimidine-5-carboxylic acid methyl ester; 1072944-54-7; Methyl 4-cyclopropyl-2-morpholin-4-ylpyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-Cyclopropyl-2-Morpholinopyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.