Description

5-Bromo-n-(Diphenylmethylene)-2-Pyrimidinamine is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyrimidine core and diphenylmethylene protecting group. This compound is critical for enabling complex synthetic routes in medicinal chemistry, particularly in the development of kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and scale-up of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic scaffolds.
• Agrochemical Development: Serves as a precursor in the research of novel crop protection agents.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	5-Bromo-n-(Diphenylmethylene)-2-Pyrimidinamine
CAS No.	1072850-89-5
Molecular Formula	C17H12BrN3
Molecular Weight	338.20 g/mol
Synonyms	5-Bromo-2-[(diphenylmethylene)amino]pyrimidine; 2-Pyrimidinamine, 5-bromo-N-(diphenylmethylene)-; 5-Bromo-N-(diphenylmethylene)pyrimidin-2-amine; 5-Bromo-2-(diphenylmethylenamino)pyrimidine; 5-Bromo-2-[(E)-diphenylmethylideneamino]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-(Diphenylmethylene)-2-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.