Description

5-Iodo-7-(Trifluoromethyl)Indoline-2,3-Dione is a high-value, multi-functional heterocyclic building block. This compound is significant for its unique molecular architecture, combining an iodine substituent with a trifluoromethyl group on an isatin core, which is highly sought after in advanced synthetic chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex molecules for drug discovery programs, particularly in oncology and CNS disease research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the halogenated isatin scaffold.
• Material Science: Acts as a building block for organic electronic materials, dyes, and pigments due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a probe or labeling agent in biochemical assays and proteomics studies.
• Academic & R&D: Utilized in methodological development and synthetic organic chemistry research at universities and corporate R&D centers.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	5-Iodo-7-(Trifluoromethyl)Indoline-2,3-Dione
CAS No.	1067187-88-5
Molecular Formula	C9H3F3INO2
Molecular Weight	340.03 g/mol
Synonyms	5-Iodo-7-(trifluoromethyl)isatin; 5-Iodo-7-trifluoromethyl-1H-indole-2,3-dione; 7-(Trifluoromethyl)-5-iodoisatin; 5-Iodo-7-trifluoromethylisatin; 1H-Indole-2,3-dione, 5-iodo-7-(trifluoromethyl)-; 5-Iodo-7-trifluoromethylindoline-2,3-dione
EINECS	Contact for details

Quality Control

Our 5-Iodo-7-(Trifluoromethyl)Indoline-2,3-Dione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.