Description

2-Benzyl-6,7,8,9-Tetrahydro-5H-Pyrimido[4,5-D]Azepine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in academic and industrial R&D labs.
• Process Chemistry & Scale-Up: Used in the optimization and pilot-scale production of APIs, where consistent quality and reliable supply are paramount.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocyclic chemistry.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	2-Benzyl-6,7,8,9-Tetrahydro-5H-Pyrimido[4,5-D]Azepine
CAS No.	1065110-62-4
Molecular Formula	C17H19N3
Molecular Weight	265.35 g/mol
Synonyms	2-Benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine; 5H-Pyrimido[4,5-d]azepine, 2-benzyl-6,7,8,9-tetrahydro-; 2-Benzyl-5,6,7,8-tetrahydropyrimido[4,5-d]azepine; Pyrimidoazepine derivative CAS 1065110-62-4
EINECS	Contact for details

Quality Control

Our 2-Benzyl-6,7,8,9-Tetrahydro-5H-Pyrimido[4,5-D]Azepine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your specifications. Our quality commitment supports applications requiring GMP-grade starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.