Description

3,4,6-Trifluoro-2-Iodoaniline is a high-purity, multi-functional halogenated aniline derivative, distinguished by its unique trifluoro and iodo substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated and iodinated active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic components in electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to construct complex biaryl systems.
• Fluorinated Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where fluorine substitution alters light absorption and color fastness properties.
• Research & Development: A valuable reagent for academic and industrial R&D in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	3,4,6-Trifluoro-2-Iodoaniline
CAS No.	1065101-52-1
Molecular Formula	C6H3F3IN
Molecular Weight	288.99 g/mol
Synonyms	2-Iodo-3,4,6-trifluoroaniline; 3,4,6-Trifluoro-2-iodobenzenamine; 2-Amino-1,3,5-trifluoro-4-iodobenzene; Benzenamine, 3,4,6-trifluoro-2-iodo-; 1065101-52-1; 3,4,6-Trifluoro-2-iodoaniline; 2-Iodo-3,4,6-trifluorophenylamine
EINECS	Contact for details

Quality Control

Our 3,4,6-Trifluoro-2-Iodoaniline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.