Description

3-Fluoro-2-Methyl-5-(Trifluoromethyl)Aniline is a high-purity fluorinated aniline derivative, a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, imparts significant electronic and steric properties, making it invaluable for modifying the pharmacokinetic profiles of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to introduce fluorine atoms for enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorination improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic diamines and other components in electronic display materials.
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a precursor for heterocyclic compounds.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated colorants with improved fastness and performance.

Basic Information

Item	Detail
Product Name	3-Fluoro-2-Methyl-5-(Trifluoromethyl)Aniline
CAS No.	1065073-89-3
Molecular Formula	C8H7F4N
Molecular Weight	193.14 g/mol
Synonyms	5-(Trifluoromethyl)-3-fluoro-2-methylaniline; 2-Methyl-3-fluoro-5-(trifluoromethyl)aniline; 3-Fluoro-2-methyl-5-(trifluoromethyl)benzenamine; 3-Fluoro-2-methyl-alpha,alpha,α-trifluoro-p-toluidine; Benzenamine, 3-fluoro-2-methyl-5-(trifluoromethyl)-; 1065073-89-3; 3-Fluoro-2-methyl-5-trifluoromethylaniline
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-Methyl-5-(Trifluoromethyl)Aniline is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its amine functionality and light-sensitive nature, prolonged exposure to air and light should be avoided.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.