Description

tert-Butyl 4-Chloro-5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate is a high-value heterocyclic building block essential for modern pharmaceutical research and development. This compound serves as a critical synthetic intermediate in the construction of complex molecules, particularly kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Organic Synthesis Building Block: Used in medicinal chemistry for the construction of complex pyrrolopyrimidine scaffolds, a privileged structure in drug discovery.
• Research & Development (R&D): Employed in academic and industrial R&D labs for exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Serves as an intermediate in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: Can be used to develop probes for studying biological mechanisms and enzyme functions in biochemical assays.

Basic Information

Product Name	tert-Butyl 4-Chloro-5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate
CAS No.	1060816-79-6
Molecular Formula	C11H12ClN3O2
Molecular Weight	253.68 g/mol
Synonyms	4-Chloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester; tert-Butyl 4-chloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine-6-carboxylate; 4-Chloro-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid 1,1-dimethylethyl ester; 1060816-79-6; 4-Chloro-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid 1,1-dimethylethyl ester; 4-Chloro-5H-pyrrolo[3,4-d]pyrimidine-6(7H)-carboxylic acid, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Chloro-5H-Pyrrolo[3,4-D]Pyrimidine-6(7H)-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the rigorous demands of pharmaceutical R&D. All products are supported by comprehensive analytical data. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.