Description

Ethyl 2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate is a high-purity, heterocyclic organic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the construction of complex molecules targeting various disease pathways. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted cancer therapies, particularly kinase inhibitors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Employed in the development of tool compounds for studying enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic and organic chemistry.

Basic Information

Product Name	Ethyl 2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate
CAS No.	1060816-62-7
Molecular Formula	C9H8ClN3O2
Molecular Weight	225.63 g/mol
Synonyms	2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid ethyl ester; Ethyl 2-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate; 2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid, ethyl ester; 6-Ethoxycarbonyl-2-chloro-7H-pyrrolo[2,3-d]pyrimidine; 2-Chloro-6-(ethoxycarbonyl)-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ISO standards for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.