Description

5-Bromo-2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced pharmaceutical synthesis. Its unique halogenated pyrrolopyrimidine structure makes it an indispensable intermediate for medicinal chemists developing targeted small-molecule therapies. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of novel kinase inhibitors and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• Biochemical Probe Development: Serves as a core scaffold for creating tool compounds to study specific biological pathways and protein functions.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for the production of Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Academic Research: Employed in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery methodologies.

Basic Information

Product Name	5-Bromo-2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1060816-58-1
Molecular Formula	C6H3BrClN3
Molecular Weight	232.47 g/mol
Synonyms	5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine; 2-Chloro-5-bromo-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 5-bromo-2-chloro-; 5-Bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine; 1060816-58-1; 5-Br-2-Cl-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to meet the stringent requirements of pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.