Description

2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key synthetic precursor for the development of novel pharmaceutical agents, particularly in kinase inhibitor research and other targeted therapeutic areas. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and commercial route development for active pharmaceutical ingredients (APIs).
• Bioconjugation: The carboxylic acid moiety allows for further functionalization and conjugation, useful in probe and linker chemistry.
• Agrochemical Research: Potential application in the discovery of new herbicides or fungicides, leveraging its heterocyclic core.
• Academic Research: Utilized in universities and research institutes for exploring new chemical reactions and biological mechanisms.

Basic Information

Product Name	2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid
CAS No.	1060816-55-8
Molecular Formula	C7H4ClN3O2
Molecular Weight	197.58 g/mol
Synonyms	2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid; 2-Chloro-5-carboxy-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine-5-carboxylic acid, 2-chloro-; 2-Chloro-1H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid; 2-Chloro-7-azaindole-5-carboxylic acid; 2-Chloro-1,7-dihydro-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.