Description

4-Chloro-2-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring both a chloro and a trifluoromethyl substituent on a fused pyrrolopyrimidine scaffold, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Serves as a versatile precursor in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrrolopyrimidine core.
• Material Science: Used in the research and development of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a molecular probe or a scaffold for designing chemical libraries in drug discovery and target identification studies.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	4-Chloro-2-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS No.	1060815-85-1
Molecular Formula	C7H3ClF3N3
Molecular Weight	221.57 g/mol
Synonyms	4-Chloro-2-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-2-(trifluoromethyl)-; 4-Chloro-2-trifluoromethyl-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-2-(trifluoromethyl)pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.