Description

Methyl5-Bromo-2-(Methylsulfonyl)Pyrimidine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is essential for research and development chemists and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for scale-up and manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its pyrimidine core structure.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds due to its reactive bromo and methylsulfonyl groups.
• Material Science Research: Investigated as a monomer or precursor for functional materials and liquid crystals.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	Methyl5-Bromo-2-(Methylsulfonyl)Pyrimidine-4-Carboxylate
CAS No.	1060795-14-3
Molecular Formula	C8H7BrN2O4S
Molecular Weight	307.12 g/mol
Synonyms	Methyl 5-bromo-2-(methylsulfonyl)pyrimidine-4-carboxylate; 5-Bromo-2-(methylsulfonyl)pyrimidine-4-carboxylic acid methyl ester; 4-Pyrimidinecarboxylic acid, 5-bromo-2-(methylsulfonyl)-, methyl ester; Methyl 5-bromo-2-methanesulfonylpyrimidine-4-carboxylate; 1060795-14-3
EINECS	Contact for details

Quality Control

Every batch of Methyl5-Bromo-2-(Methylsulfonyl)Pyrimidine-4-Carboxylate is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.