Description

2-(4-(Piperazin-1-Yl)Phenyl)Pyrimidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is essential for research and development chemists, process scale-up teams, and manufacturers in the global pharmaceutical and biotechnology sectors seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Bioconjugation & Probe Synthesis: Serves as a versatile linker or functional group for creating biochemical probes and diagnostic agents.
• Academic Research: Employed in university and institutional labs for investigating novel heterocyclic chemistry and pharmacological mechanisms.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	2-(4-(Piperazin-1-Yl)Phenyl)Pyrimidine Hydrochloride
CAS No.	1056624-11-3
Molecular Formula	C14H17N5·HCl
Molecular Weight	291.78 g/mol
Synonyms	2-[4-(Piperazin-1-yl)phenyl]pyrimidine hydrochloride; 2-(4-Piperazin-1-ylphenyl)pyrimidine HCl; 2-(4-(1-Piperazinyl)phenyl)pyrimidine hydrochloride; 1056624-11-3; UNII-6Q8F0I5Y8F; 6Q8F0I5Y8F; BDBM50382895; AKOS025310991; ZINC000004079756; 2-(4-Piperazinophenyl)pyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-(Piperazin-1-Yl)Phenyl)Pyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.