Description

3-Fluoro-4-(Tetrahydro-2H-Pyran-4-Yloxy)Aniline is a high-purity, advanced pharmaceutical intermediate characterized by its unique aniline derivative structure with a fluorine substituent and a tetrahydropyranyloxy group. This compound is of significant value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling precise molecular modifications. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel small-molecule drugs, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and stability.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic compounds and fine chemicals.
• Material Science Research: Investigated for potential applications in the development of specialty polymers and functional materials.

Basic Information

Product Name	3-Fluoro-4-(Tetrahydro-2H-Pyran-4-Yloxy)Aniline
CAS No.	1054316-88-9
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	3-Fluoro-4-[(oxan-4-yl)oxy]aniline; 4-Amino-2-fluoro-1-(tetrahydro-2H-pyran-4-yloxy)benzene; 3-Fluoro-4-(tetrahydropyran-4-yloxy)phenylamine; 1054316-88-9; 3-Fluoro-4-(oxan-4-yloxy)aniline; Benzenamine, 3-fluoro-4-[(tetrahydro-2H-pyran-4-yl)oxy]-
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-(Tetrahydro-2H-Pyran-4-Yloxy)Aniline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities that follow cGMP principles where applicable. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.