Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-7-[4-[2-(3-Fluorophenyl)Acetyl]-1-Piperazinyl]-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is a key synthetic precursor in the development of novel fluoroquinolone antibiotics, valued for its precise molecular architecture which is critical for imparting targeted biological activity. It is primarily required by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical suppliers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: Critical building block in the synthesis of next-generation fluoroquinolone antibiotic candidates.
• Active Pharmaceutical Ingredient (API) Development: Used in research and process development for novel antibacterial agents.
• Biochemical Research: Serves as a reference standard or probe compound in microbiological and pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for medicinal chemistry and drug discovery programs.
• Process Chemistry Optimization: Employed in scaling up and optimizing synthetic routes for cost-effective API production.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-7-[4-[2-(3-Fluorophenyl)Acetyl]-1-Piperazinyl]-1,4-Dihydro-4-Oxo-
CAS No.	1054130-31-2
Molecular Formula	C24H21F2N3O3
Molecular Weight	437.44 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-7-[4-[2-(3-fluorophenyl)acetyl]piperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(3-fluorophenacyl)piperazin-1-yl)quinoline-3-carboxylic Acid; 7-[4-[2-(3-Fluorophenyl)acetyl]-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; Intermediate for Antibiotic Development; Fluoroquinolone Intermediate; CAS 1054130-31-2
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, related substances, and residual solvents are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.