Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-(3-Methyl-4-Nitrobenzoyl)-1-Piperazinyl]-4-Oxo- is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This complex heterocyclic compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is essential for R&D chemists and manufacturers in the pharmaceutical industry seeking to develop or produce next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of novel fluoroquinolone antibiotics.
• Antibacterial Drug Development: Serves as a core scaffold for research into new antibacterial agents targeting resistant bacterial strains.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for the construction of complex molecules with potential biological activity.
• Process Chemistry & Scale-Up: Employed in the optimization and commercial-scale manufacturing processes for target APIs.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and drug development services.
• Reference Standard: Can be used as an analytical standard for quality control and regulatory submissions in pharmaceutical production.

Basic Information

Item	Detail
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-(3-Methyl-4-Nitrobenzoyl)-1-Piperazinyl]-4-Oxo-
CAS No.	1054110-78-9
Molecular Formula	C24H21FN4O5
Molecular Weight	464.45 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[4-(3-methyl-4-nitrobenzoyl)-1-piperazinyl]-4-oxo-3-quinolinecarboxylic acid; 7-[4-(3-Methyl-4-nitrobenzoyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; Garenoxacin Intermediate; Garenoxacin Related Compound; AM-1155 Intermediate; T-3811 Intermediate; 3-Quinolinecarboxylic acid derivative; Fluoroquinolone piperazine intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a dry environment and opened under inert atmosphere conditions when handling is required for prolonged periods.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.